Quinolines and derivatives
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Filtered Search Results
eMolecules ChemScene / 4-Bromo-6-nitroquinoline / 100mg / 694122565 / CS-0041424 / 0.000 / 860195-53-5 / MFCD08688607 / 253.055 / C9H5BrN2O2
ChemScene / 4-Bromo-6-nitroquinoline / 100mg / 694122565 / CS-0041424 / 0.000 / 860195-53-5 / MFCD08688607 / 253.055 / C9H5BrN2O2
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eMolecules 8-Hydroxy-6-nitroquinoline | 16727-28-9 | MFCD00466084 | 1g
Combi-Blocks, Inc. | 8-Hydroxy-6-nitroquinoline | 1g | 603144264 | QB-4179 | 95.000 | 16727-28-9 | MFCD00466084 | 190.158 | C9H6N2O3
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Selleck Chemical LLC 4-Nitroquinoline 1-oxide
4-Nitroquinoline 1-oxide (4-Nitroquinoline-N-oxide 4-NQO 4NQO 4Nqo NQO NQNO) is a highly carcinogenic model chemical that induces mutations in bacteria fungi and animals through the formation of bulky purine adducts 4-Nitroquinoline 1-oxide can be used to induce animal models of Squamous Cell Carcinoma
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Accela Chembio Inc 5-nitroquinoline | 100g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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5-nitroquinoline | 100g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 25 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It can induce apoptosis and is used for malaria research.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker with an IC50 of 19.9 μM
- Induces apoptosis
- Can be used for malaria research
- Shows cytotoxicity against MES-SA cells
- Shows effects on the PTZ-induced seizure threshold in vivo
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Medchemexpress LLC Quinine sulfate hydrate | 6119-70-6 | 99.97% | 409.48 | 25 G
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Quinine sulfate hydrate is an orally active alkaloid extracted from cinchona bark, primarily used in anti-malarial studies. It also functions as a potassium channel inhibitor, inhibiting WT mouse Slo3 (KCa5.1) channel currents.
- Orally active alkaloid
- Extracted from cinchona bark
- Used in anti-malarial studies
- Potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits DENV proliferation and reduces viral RNA/protein levels
- Shows tumor-suppressing effects
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Chemscene CHEMSCENE
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5000579330 HYDROQUINIDINE 10G
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Chemscene CHEMSCENE
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5000579432 HYDROQUINIDINE 25G
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Medchemexpress LLC Cinchonine ((8R,9S)-cinchonine) | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 500g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Apexbio Technology LLC Quinidine 56-54-2 50mg
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Quinidine (CAS 56-54-2) is a small-molecule inhibitor targeting sodium (Na ) and potassium (K ) ion channels It is designed to inhibit these ion channel currents thereby modulating cardiac electrophysiological processes Quinidine exerts its biological activity primarily through inhibition of Na and K currents In in vitro studies quinidine demonstrates inhibitory activity with an IC50 of approximately 41 M on the transient outward potassium current (Ik) at a membrane potential of 0 mV Based on these pharmacological properties quinidine holds research potential in the fields of cardiac electrophysiology ion channel pharmacology drug metabolism and drug-drug interaction mechanisms
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Medchemexpress LLC Quinine hydrochloride dihydrate | 6119-47-7 | 99.7% | 10 G
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Quinine hydrochloride dihydrate is an orally active compound primarily used in anti-malarial studies. It functions as a potassium channel inhibitor, specifically targeting WT mouse Slo3 (KCa5.1) channel currents. This compound has also demonstrated effects against Dengue virus proliferation in HepG2 cell lines and exhibited some tumor-suppressing activity in skin cancer models.
- Acts as a potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits DENV proliferation and cytostatic effects in HepG2 cell lines
- Reduces viral DENV RNA and protein levels
- Shows tumor-suppressing effects on skin cancer in mice
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5000579323 RESIQUIMOD 5G
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5000579530 RESIQUIMOD 25MG
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5000580069 RESIQUIMOD 250MG
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Selleck Chemical LLC Resiquimod
Resiquimod (R-848 S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF- IL-6 and IFN- Resiquimod reduces hepatitis C virus (HCV) infection Phase 2
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