Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,051 – 1,065 of 5,526 results

1,051

Ambeed AMBEED

5000870746 2-CHLORO-8-NITROQUINOLINE 1GR

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1,052

eMolecules 2757730-33-7 | ETHYL 4-AMINOQUINOLINE-6-CARBOXYLATE HYDROCHLORIDE | AstaTech252.700 | C12H13ClN2O2 | 95.000 | Cl.CCOC(=O)c1ccc2nccc(N)c2c1 | 0.1g | 746294409

ETHYL 4-AMINOQUINOLINE-6-CARBOXYLATE HYDROCHLORIDE | AstaTech | 2757730-33-7252.700 | C12H13ClN2O2 | 95.000 | Cl.CCOC(=O)c1ccc2nccc(N)c2c1 | 0.1g | 746294409

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1,053

Aobchem Trimethyl(3 4 5-trifluorophenyl)silane | 95% | CAS 1860380-19-3 | C9H11F3Si | 500mg

Trimethyl(3 4 5-trifluorophenyl)silane | 95% | CAS 1860380-19-3 | C9H11F3Si | 500mg

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1,054

Medchemexpress LLC M-PEG3-AMINE 5G

5000203091 M-PEG3-AMINE 5G

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1,055

Aobchem 6-Trimethyl-2-pyridineacetonitrile | 95% | CAS 878744-13-9 | C10H12N2 | 1g

6-Trimethyl-2-pyridineacetonitrile | 95% | CAS 878744-13-9 | C10H12N2 | 1g

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1,056

Apexbio Technology LLC RO4929097(Synonyms: RO-4929097, RO 4929097, Gamma-Secretase Inhibitor RO4929097, RO4929097 γ-secretase inhibitor), 200mg, CAS: 847925-91-1.

RO4929097 (CAS 847925-91-1) is a potent selective small-molecule inhibitor of -secretase an essential protease in the Notch signaling pathway It inhibits -secretase with high specificity (IC50 4 nM EC50 5 nM) showing minimal inhibitory activity against closely related proteases and over 100-fold selectivity versus a broad spectrum of other proteases By preventing Notch receptor cleavage and subsequent signaling activation RO4929097 suppresses proliferation and tumorigenesis across various tumor models including melanoma breast colorectal pancreatic and lung cancers Clinical studies have assessed RO4929097 alone or combined with other anticancer agents for advanced solid tumors

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1,057

Apexbio Technology LLC Ganetespib (STA-9090)(Synonyms: STA-9090, Ganetespib, STA9090, STA 9090), 200mg, CAS: 888216-25-9.

Ganetespib (STA-9090 CAS 888216-25-9) is a small-molecule inhibitor targeting heat shock protein 90 (Hsp90) It binds competitively to the ATP-binding pocket located at the N-terminal region of Hsp90 disrupting its chaperone activity and subsequently causing degradation of client proteins involved in tumor growth and survival Structurally distinct from geldanamycin-derived inhibitors Ganetespib features a triazolone moiety Preclinical studies have demonstrated antitumor activity across various cancer cell types including lung prostate colon breast cancers melanoma and leukemia highlighting its therapeutic potential for cancer research

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1,058

TARGETMOL CHEMICALS INC VIGABATRIN 25MG

502693609 VIGABATRIN 25MG

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1,059

ARCTOM SCIENTIFIC E-1-PIPERIDINO-3-3-QUINOLIN

NC3720333 E-1-PIPERIDINO-3-3-QUINOLIN

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1,060

Aobchem 7-Bromo-8-methylquinoline | ≥97% | CAS 809248-61-1 | C10H8BrN | 5g

7-Bromo-8-methylquinoline | ≥97% | CAS 809248-61-1 | C10H8BrN | 5g

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1,061

Aobchem 4-Bromo-1-(1-ethoxy-ethyl)-1H-pyrazole | ≥97% | CAS 1024120-52-2 | C7H11BrN2O | 5g

4-Bromo-1-(1-ethoxy-ethyl)-1H-pyrazole | ≥97% | CAS 1024120-52-2 | C7H11BrN2O | 5g

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1,062

Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML

Trovafloxacin mesylate is the mesylate salt of trovafloxacin, a broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV. It is used in research to study antibacterial activity and pannexin 1 (PANX1) channel function and inhibition.

Broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV.
Also reported as a pannexin 1 (PANX1) inhibitor with an IC50 around 4 μM.
Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for experimental flexibility.
High purity: 99.8% (HPLC) as reported by supplier.
CAS number 147059-75-4; molecular weight 512.46 g/mol.

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1,063

Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG

Deferoxamine mesylate (Standard) is an analytical standard intended for research and analytical applications. It functions as an iron chelator, binding to Fe(III) and other metal cations, thereby reducing iron accumulation and deposition in tissues. This compound also upregulates HIF-1α levels and exhibits good antioxidant activity, along with anti-proliferative activity that can induce apoptosis and autophagy in cancer cells.

Used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research
Serves as a reference standard for assays
Frequently utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS

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1,064

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 5 MG

Ruboxistaurin mesylate is an orally active, ATP-competitive, and selective protein kinase C beta (PKCβ) inhibitor used in preclinical research on diabetic complications, retinal/eye disorders, and cardiovascular disease. It is supplied as a solid with high reported purity and is soluble in DMSO for in vitro applications.

Selective PKCβ inhibitor with low-nanomolar potency.
Orally active small molecule suitable for in vitro and in vivo studies.
High reported purity (~99.9%) for research applications.
Solid form, orange to red color, easy handling and storage.
Soluble in DMSO at 50 MG/ML (88.55 mM); ultrasonic assistance may be required.
Storage guidance: 4°C sealed; in solvent: -80°C (6 months), -20°C (1 month).

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1,065

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 1 MG

Dosimertinib-d5 (mesylate) is a potent, orally active Epidermal Growth Factor Receptor (EGFR) inhibitor. It decreases the expression of p-EGFR and p-ERK protein levels, demonstrating antiproliferative and anti-tumor activity. It has potential for research into non-small-cell lung cancer (NSCLC).

Potent and orally active EGFR inhibitor.
Decreases p-EGFR and p-ERK protein levels.
Antiproliferative and anti-tumor activity.
Suitable for use as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Decreases p-EGFR and p-ERK protein levels in A431 and H1975 cells in a dose-dependent manner.
Shows anti-tumor activity in BALB/c nude mice with H1975 xenograft model.
Soluble in DMSO at 100 mg/mL (166.46 mM), requiring ultrasonic and warming to 80°C.

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Quinolines and derivatives

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Medchemexpress LLC M-PEG3-AMINE 5G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC M-PEG3-AMINE 5G

Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML

Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 5 MG

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 1 MG